• Determine the accuracy of the NTX wireless monitoring system alerts
• Evaluate patient compliance with wearing device
• Determine false alarm rates

Approximately 150 patients will have wireless monitors attached to their arm. They will have their vital signs filtered through software that generates alerts and records data. The alert engine will produce pager and application based pop-up alerts which will be sent to the research nurse. Low and high limit alarms will be set according to the published guidelines (Hillman, K. et. Al., Resuscitation 48(2): 105-10, 2001) and adjusted at will by the response team.

During this portion of the study, the following research related procedures will be performed:

• begin continuous vital signs monitoring (BP - 1x per hour, 3 lead ECG -continuous, HR - continuous, SpO2 - continuous)
• PI or Co-PI will review each alert that's generated. The clinical significance will be determined and recorded in the study database
• Record patient's signs and symptoms daily
• Assess concomitant
• Assess AE's, SAEs

Inclusion Criteria:

• Ability to give written informed consent
• Patients that are hospitalized for longer than 24 hours and are located on the 4th, 5th, or 6th floor of the Vanderbilt University Medical Center Round Wing
• Patients must be ≥18 years of age

Exclusion Criteria:

• ICU patients
• Female subjects who are pregnant
• Patients < 18 years of age
• Patients that have a contradiction for continuous Blood Pressure monitoring

Participants will be recruited in the Vanderbilt University Medical Center pre-operative clinic or in the Round Wing, after the effects of anesthesia have worn off. Before performing any trial-related procedures, written Informed Consent and HIPAA authorization will be obtained.