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| Name | Class |
|---|---|
| Office of Minority Health | UNKNOWN |
| Mississippi Institute for Improvement of Geographic Minority Health | UNKNOWN |
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The goal of this study is to examine the activation of markers of endothelial and cardiovascular dysfunctions, from women with high-risk pregnancies. Information from this study will hopefully provide enough information to determine a link between race, the advent of high risk pregnancies and cardiovascular markers. With this information it might be possible to intervene with approved pharmacological treatments.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A, 1, I | Caucasian women without preeclampsia or PIH, delivering their first child | ||
| A, 1, II | Caucasian women with preeclampsia or PIH, delivering their first child | ||
| A, 2, I | African-american women without preeclampsia or PIH, delivering their first child | ||
| A, 2, II | African-American women with preeclampsia or PIH, delivering their first child | ||
| B, 1, I | Caucasian women without preeclampsia or PIH, delivering at least their second child | ||
| B, 1, II | Caucasian women with preeclampsia or PIH, delivering at least their second child | ||
| B, 2, I | African-american women without preeclampsia or PIH, delivering at least their second child |
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| Measure | Description | Time Frame |
|---|---|---|
| Nitric oxide and Endothelin-1 levels | 48 hours after tissue collection |
| Measure | Description | Time Frame |
|---|---|---|
| Nitric oxide isoforms and Endothelin-1 receptor activation based on primary outcome | within 6 months from tissue collection |
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Inclusion Criteria:
Exclusion Criteria:
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Women delivering babies at the University of MS Medical Center
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| Name | Affiliation | Role |
|---|---|---|
| Kedra L Wallace, PhD | Obstetrics & Gynecology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of MS Medical Center | Jackson | Mississippi | 39216 | United States |
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| ID | Term |
|---|---|
| D011225 | Pre-Eclampsia |
| ID | Term |
|---|---|
| D046110 | Hypertension, Pregnancy-Induced |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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Placental Tissue
| B, 2, II | African-american women with preeclampsia or PIH, delivering at least their second child |