Safety and Efficacy Study of Gatifloxacin Compared With Ciprofloxacin in Patients With Acute Bacterial Corneal Ulcers
ClinicalTrials.gov ID
NCT00651586
Lead Sponsor
AllerganINDUSTRY
Overall Status
Completed
Study Type
Interventional
Phase
Phase 2
Enrollment
129Actual
Last Update Posted
Jul 29, 2008Estimated
Start Date
Oct 2003
Primary Completion Date
Apr 2005Actual
Completion Date
Apr 2005Actual
Brief Summary
This study evaluates the safety and efficacy of gatifloxacin 0.3% ophthalmic solution compared with ciprofloxacin 0.3% ophthalmic solution in patients with acute bacterial corneal ulcers
Acute Bacterial Corneal Ulcers
Bacterial Keratitis
Gatifloxacin 0.3% ophthalmic solution
Ciprofloxacin 0.3% ophthalmic solution
Ages Eligible for Study
Child (0-17)Adult (18-64)Older Adult (65+)
Sexes Eligible for Study
All
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Clinical diagnosis in one eye only of an acute bacterial corneal ulcer (>1mm)
Exclusion Criteria:
Corneal ulcer that in the opinion of the investigator had to be treated with fortified antibiotics, or multiple antibiotics, or anti-infectives other than study medication