A Study Comparing the Safety and Efficacy of Ziprasidone and Risperidone for the Treatment of Chronic Schizophrenia

Ziprasidone Versus Risperidone In The Treatment Of Chronic Schizophrenia: A Six Months, Double Blind Randomized, Parallel Group Study

The purpose of this study is to compare the safety of ziprasidone and risperidone for the treatment of chronic schizophrenia. The primary purpose is to differentiate the effects of ziprasidone and risperidone on extrapyramidal side effects and the secondary purpose is to compare their tolerability and efficacy.

Inclusion Criteria:

• Diagnosis of schizophrenia
• CGI-S score of 4 or less at baseline

Exclusion Criteria:

• Concurrent antipsychotic treatment
• Treatment with antidepressants or mood stabilizers within 2 weeks of randomization
• Acute exacerbation of schizophrenia within 3 months of baseline