Topical Imiquimod in Conjunction With Nd:YAG Laser for Tattoo Removal

Topical Imiquimod in Conjunction With Nd:YAG Laser for Tattoo Removal

The purpose of this study is to evaluate the efficacy of tattoo removal using topical imiquimod, 5% cream in conjunction with the 1064nm Nd:YAG laser. This procedure for tattoo removal will be compared to a laser removal alone.

Inclusion criteria includes: patients of both genders with Fitzpatrick skin types I-IV who are 18-65 years of age and who has 2 tattoos from 2 to 10 cm in diameter, of similar age which contains black and/or blue ink in areas that can be covered. Exclusion criteria includes: tattoos in chronically sun exposed areas, larger than 25 cm2,pregnancy,breast feeding state, immunosuppressed patients, history of autoimmune or connective tissue disorders, hypersensitivity to imiquimod, active sunburn, current tan, use of coumadin, aspirin , vitamin E or non-steroidal anti-inflammatory agents for the past 10 days.

Inclusion Criteria:

• 2 tattoos no larger than 25cm2, professionally made, with approximately the same age, containing blue/black ink.

Exclusion Criteria:

• Hypersensitivity to imiquimod
• Current sun tan
• Use of vitamin E, non-steroid anti-inflammatory drugs, coumadin or aspirin for the past 10 days
• Amateur tattoos
• Pregnancy
• Breast-feeding status
• Immunosuppression
• Auto-immune diseases.