A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Inhaled Montelukast (MK-0476) in Participants With Mild or Moderate Asthma (MK-0476-380 AM3)(COMPLETED)

A Sequential, 3-Part, Double-Blind, Randomized, Placebo-Controlled, Single-Rising-Dose and Rising-Multiple-Dose Study in Healthy Subjects and Mild or Moderate Asthmatic Patients to Evaluate the Safety, Tolerability, and Pharmacokinetics of Inhaled MK-0476

A study to evaluate the safety, tolerability and pharmacokinetics of inhaled Montelukast (MK-0476) in participants with mild or moderate asthma.

Inclusion Criteria:

• Male or female between the ages of 18 and 65
• Must have mild or moderate asthma (Part III only)
• Nonsmoker for at least 6 months

Exclusion Criteria:

• History of stroke, chronic seizures or major neurological disorder
• You are nursing
• Drink more than 3 glasses of alcohol a day
• Have allergy to or not able to tolerate lactose
• Have a history of drug abuse in the last 5 years
• Drink more than 6 beverages containing caffeine a day
• Have had surgery, donated blood or participated in another investigational study in the last 4 weeks