The purpose of this study is to evaluate and determinate the functional abilities in Rett syndrome conforming to the established Pediatric Evaluation of Disability Inventory (PEDI).

Rett syndrome (RS) is a progressive neurological disturbance of genetic cause that affects females almost exclusively. It is caused by mutations, usually sporadic, of the MECP2 gene located in the X chromosome. In consequence to the serious cognitive and motor compromise, the RS patients have great difficulty in accomplishing day-to-day tasks. The objective of this work is to evaluate the functional abilities in RS to help therapists in theirs treatments programs.

Inclusion Criteria:

• Patients with Rett syndrome that matched the criteria for the classic form of the disease

Exclusion Criteria:

• Any other disease;
• Rett syndrome associated with other disease
• Rett syndrome that not that matched the criteria for the classic form of the disease

This study investigated only patients with Rett syndrome that matched the criteria for the classic form of the disease