Treatment of Impaired Glucose Tolerance in Pregnancy

Randomized Controlled, Multicenter Study Evaluating Treatment of Glucose Intolerance in Pregnancy

The purpose of this study is to evaluate if treatment (insulin or diet) of pregnant women with impaired glucose tolerance (75-g OGTT with a fasting P-gluc <7.0 mmol/l and 2 h P-gluc >10.0 and <12.2 mmol/l) close to normoglycemia reduces children´s birth weight and neonatal morbidity. There will be a focus on treatment according to specific goals and separate follow-up regimes for the children and women post partum.

Inclusion Criteria:

• Women with 75g OGTT result : fasting capillary plasma <=7.0 mmol/l and/or 2 h value >= 12.2 mmol/l

Exclusion Criteria:

• Multiple pregnancy
• Pregestational Diabetes