Relationship Between Erythropoietin Administration and Stress Responses in Trauma Patients

Relationship Between Clinical Recovery and Oxidative Stress and Inflammation Following Usage of Erythropoietin in Admitted Traumatic Patient In Intensive Care Unit

The purpose of this study is to determine whether Erythropoietin decrease stress responses and inflammation in trauma patient.

Transfusion of blood products has many disadvantages. Erythropoietin is used to increase red blood cells production and decrease such disadvantages.In some studies anti inflammatory effects is shown for Erythropoietin.

One of the most problems in the intensive care unit is stress response. we are going to evaluate effects of erythropoietin on oxidative stress and inflammation in trauma patient in intensive care unit.

Inclusion Criteria:

• All multiple trauma patients>16 years with informed consent

Exclusion Criteria:

• Hypertension
• Allergy
• Erythroid leukemia
• Pregnancy and breast feeding
• Pre operative patient
• Severe cardiovascular and cerebrovascular diseases
• Thromboembolic disorders