Fenoldopam and Acute Renal Failure

Efficacy of Fenoldopam in Reducing the Need for Renal Replacement Therapy After Cardiac Surgery. A Randomized Controlled Study.

Patients undergoing cardiac surgery could develop postoperative acute renal failure requiring renal replacement therapy.

Fenoldopam, already used for patients with hypertensive emergencies, could improve renal function in critically ill patients with or at risk for acute renal failure.

Inclusion Criteria:

• adult patients
• who underwent cardiac surgery
• have Risk of Acute Renal Failure (R of RIFLE score)

Exclusion Criteria:

• glaucoma
• already on renal replacement therapy
• study drug in the past 30 days
• inclusion in other protocols