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The purpose of this study is to see if a blood test (D-dimer) is as precise as the CT scan for the detection of clots.
A pulmonary embolism is an obstruction of the blood vessels in your lungs usually due to a blood clot that travels to the lungs usually from the leg. Research has shown that the results of a specific blood test (D-dimer) can be used instead of a CT scan to diagnose clots. D-dimer is a valuable diagnostic marker in either detecting the presence of or monitoring the progress of blood clots. D-dimer assays have proven to be a beneficial diagnostic tool in the evaluation of patients with suspected pulmonary embolism (PE).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Patients to have a CT pulmonary angiogram for suspected pulmonary embolism will have a d-dimer drawn as is routinely done. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CT pulmonary angiogram and d-dimer draw | Procedure | A CT pulmonary angiogram and a d-dimer drawn within 24 hours. |
|
| Measure | Description | Time Frame |
|---|---|---|
| The negative predictive value of the d-dimer assay relative to CT pulmonary angiogram will be the primary measure of accuracy used for this purpose. | conclusion of study |
| Measure | Description | Time Frame |
|---|---|---|
| To estimate the positive predictive value, sensitivity, and specificity of the d-dimer assay relative to CT pulmonary angiogram. | conclusion of study | |
| To explore the association between the accuracy of the d-dimer assay and clinical symptoms indicating pulmonary embolism. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients coming to MSKCC Urgent care unit
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | United States |
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| Label | URL |
|---|---|
| Memorial Sloan-Kettering Cancer Center | View source |
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
| D011655 | Pulmonary Embolism |
| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D004617 | Embolism |
| D016769 | Embolism and Thrombosis |
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| conclusion of study |
| D014652 |
| Vascular Diseases |
| D002318 | Cardiovascular Diseases |