Non-Hodgin's lymphoma is curable in 76% of patients. In nonlymphoblastic lymphmas, cancer may return on average 3 months from beginning treatment and for lymphoblastic lymphomas, 6 months. To aggressively treat this cancer this study uses effective drugs in three parts:

• Induction ends on day 19
• Consolidation ends on day 38 or 42
• Maintenance may include up to 6 cycles

Inclusion Criteria:

• Non-Hodgkin's Lymphoma stages III, IV, IVA with

  1. T cell lymphomas, any primary site irrespective of LDH level
  2. large cell lymphomas, any primary site irrespective of LDH level
  3. B cell lymphomas, any primary site with initial LDH of less than 500

Exclusion Criteria:

• B cell lymphomas, any primary site with initial LDH of less than 500 and initial CNS or bone involvement