Comparison of Atrophogenic Effect of Hydrocortison 1% Cream and Pimecrolimus 1% Cream Assessed by Optical Coherence Tomography (OCT) and 20-MHz Ultrasound of Uninvolved Skin in Patients With Atopic Dermatitis

Comparison of Atrophogenic Effect of Hydrocortison 1% Cream and Pimecrolimus 1% Cream Assessed by Optical Coherence Tomography (OCT) and 20-MHz Ultrasound of Uninvolved Skin in Patients With Atopic Dermatitis

to explore the atrophogenic potentials of hydrocortison 1% cream and pimecrolimus 1% cream on unaffected forehead skin

Inclusion Criteria:

• age 18-60 years
• diagnosis of atopic dermatitis (Hanifin & Rajka Criteria)
• patients with atopic dermatitis not affecting the forehead

Exclusion Criteria:

• pregnancy / nursing mothers
• women in reproductive age without adequate contraception
• severe atopic dermatitis (IGA >= 4)
• UV-Therapy in past 4 weeks
• patients receiving any topical treatment on the face in past 6 month