This observational study compares the influence of Ringer's Lactate solution and Ringer's Acetate solution on organ function scores following severe burn injury.

In the early period following severe burn injury volume replacement with high amounts of crystalloids is necessary. In this study we compare the organ function scores of a historical patient group, treated with Ringer's Lactate solution, with an actual patient population, treated with Ringer's Acetate solution.

Inclusion Criteria:

• Age >=18 years and <80years
• Burned surface area >20% and <70%
• Burn injury < 24 hours
• Agreement to the study procedures

Exclusion Criteria:

• Burned surface area > 70%
• Expected survival time < 24 hours
• Acute or chronic heart failure NYHA III or IV
• Adult respiratory distress syndrome
• Renal failure
• Hepatic failure

patients within a 24-hours period after severe burn injury