Identification of Cardiovascular Risk Factors Linked to Renal Failure Progression

Vascular Risk Factors and Coronary Calcifications in Chronic Renal Failure Patients: Identification of Specific Factors Linked to Renal Failure Progression

The aim of this study is to appreciate the influence of renal failure progression on vasculopathy (coronary calcifications and left ventricular hypertrophy) and cardiovascular risk factors.

The aim of this study is to appreciate the relationship between:

• extension of coronary calcifications and chronic renal failure progression
• extension of coronary calcifications and levels of osteoprotegerin (bone disease marker)
• cardiovascular risk factors and coronary calcifications
• cardiovascular risk factors and existence of cardiovascular diseases

Inclusion Criteria:

• Patient who has signed the written consent form

• Patient aged > 18 and < 90 years

• Chronic renal failure defined by glomerular filtration rate (GFR)

  • group 1: GFR >90 mL/min with urinary biological abnormalities and GFR comprised between 90 and 60 mL/min
  • group 2: GFR comprised between 60 and 30 mL/min
  • group 3: GFR <30 mL/min but without dialysis therapy

Exclusion Criteria:

• Chronic renal failure patient requiring dialysis therapy