Efficacy and Safety of Insulin Detemir in Type 2 Diabetes Inadequately Controlled on OHA Therapy Alone

Comparison of Efficacy and the Safety of Insulin Detemir and Insulin NPH as add-on to Current OHA Therapy in Subjects With type2 Diabetes Mellitus

This trial is conducted in Japan. The aim of this trial is to investigate the efficacy of insulin detemir on blood glucose control in type 2 diabetes when added to current OHA treatment.

Inclusion Criteria:

• Duration of type 2 diabetes mellitus for at least one year
• Insulin naive patients
• OHA treatment for at least 12 weeks
• HbA1C between 7.5-10.0%
• Body Mass Index (BMI) below 30.0 kg/m2

Exclusion Criteria:

• Impaired renal function
• Impaired hepatic function
• Pregnant, breast-feeding (within a year after delivery), intention of becoming pregnant or not using adequate contraceptive methods