Role of Pancreatic Triglyceride Content in Beta-cell Function

Role of Pancreatic Triglyceride Content in Beta-cell Function

The study evaluates if fat accumulates in the pancreas in individuals at risk of developing obesity-related diabetes. It also evaluates if the amount of fat in the pancreas can predict the residual functional capacity of the pancreas (insulin secretion).

Inclusion Criteria:

• adults without prior history of pancreatic disease (other than diabetes)

Exclusion Criteria:

• use of unapproved medications
• contraindications to the MRI procedure
• contraindications to frequent blood draws
• pregnancy
• use of more than 2 alcoholic drinks/day