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| Name | Class |
|---|---|
| Department of Health and Human Services | FED |
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The purpose of this study is to compare the clinical effectiveness of two types of chiropractic spinal manipulation to conservative medical care for patients at least 55 years old with sub-acute or chronic low back pain (LBP).
Despite the high prevalence of LBP and the associated economic costs, disability, and lost productivity, and despite the development of several treatment guidelines, one of which recommends chiropractic spinal manipulation for some subgroups of patients with pack pain, the management of LBP remains controversial and highly variable across professions and geographic regions. Although one recent publication describes the design of chiropractic and exercise for seniors with low back or neck pain, no published studies to our knowledge, have assessed the effectiveness of chiropractic manipulation compared to medical care for older adults with sub-acute or chronic low back pain.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HVLA-SM | Experimental | High-velocity low amplitude spinal manipulation (HVLA-SM) |
|
| LVVA-SM | Experimental | Low-velocity variable amplitude spinal manipulation (LVVA-SM) |
|
| Usual Medical Care | Active Comparator | Usual medical care - (Celebrex, Aleve, Bextra, Naproxen) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HVLA-SM | Other | High-velocity low amplitude spinal manipulation (HVLA-SM) |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Roland Morris Disability Questionnaire(RMDQ). | 6 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Fear Avoidance Beliefs Questionnaire, physical subscale | 6 weeks, 3 months, 6 months | |
| Visual Analogue Scale for Pain | 6 weeks | |
| Postural Sway |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| William C Meeker, DC, M.P.H. | Palmer College of Chiropractic | Principal Investigator |
| Maria A Hondras, DC, MPH | Palmer College of Chiropractic | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Palmer Center for Chiropractic Research | Davenport | Iowa | 52803 | United States | ||
| The University of Iowa |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19539115 | Result | Hondras MA, Long CR, Cao Y, Rowell RM, Meeker WC. A randomized controlled trial comparing 2 types of spinal manipulation and minimal conservative medical care for adults 55 years and older with subacute or chronic low back pain. J Manipulative Physiol Ther. 2009 Jun;32(5):330-43. doi: 10.1016/j.jmpt.2009.04.012. | |
| 18990046 | Result |
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| ID | Term |
|---|---|
| D000068579 | Celecoxib |
| D009288 | Naproxen |
| C406224 | valdecoxib |
| ID | Term |
|---|---|
| D000096926 | Benzenesulfonamides |
| D013449 | Sulfonamides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
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| LVVA-SM |
| Other |
Low-velocity variable amplitude spinal manipulation (LVVA-SM) |
|
| Usual medical care | Drug | Celebrex: po, 200mg, qd, six weeks; Aleve: po, 220mg, bid, six weeks; Bextra: po, 10mg, qd, six weeks; Naproxen: po, 500mg, bid, six weeks. |
|
|
| 6 weeks |
| SF-36, v1, Physical Function subscale | 6 weeks |
| Posteroanterior Spinal Stiffness | 6 weeks |
| Sit-to-Stand Maneuver | 6 weeks |
| Spinal Manipulation | 6 weeks |
| Iowa City |
| Iowa |
| 52242 |
| United States |
| Hondras MA, Long CR, Haan AG, Spencer LB, Meeker WC. Recruitment and enrollment for the simultaneous conduct of 2 randomized controlled trials for patients with subacute and chronic low back pain at a CAM research center. J Altern Complement Med. 2008 Oct;14(8):983-92. doi: 10.1089/acm.2008.0066. |
| D001555 |
| Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |
| D013450 | Sulfones |
| D013457 | Sulfur Compounds |
| D011720 | Pyrazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D009280 | Naphthaleneacetic Acids |
| D009281 | Naphthalenes |
| D011084 | Polycyclic Aromatic Hydrocarbons |
| D011083 | Polycyclic Compounds |