Comparison of Two Pharmacological Treatments of Pedophilia

Comparative Controlled Clinical Trial of Two Pharmacological Treatments of Pedophilia

Sexual abuse committed on children is a major public health problem because of its frequency and its severe consequences on the mental health of victims.

Objective: to compare the therapeutic efficacy of cyproterone acetate (CPA) and leuprolide, with the hypothesis that leuprolide will be more effective.

Inclusion Criteria:

• clinical diagnosis of pedophilia
• high frequency of sexual urges and deviant behavior as demonstrated by a score equal to 8 on the scale of Rösler & Witztum (Rösler & Witztum, 1998) ;
• age: 18-60 years
• informed consent

Exclusion Criteria:

• IQ<70
• schizophrenia, schizoaffective disorder, or delusional disorder
• already receiving one of the tested drugs
• contraindication for one of the tested drugs
• no current or planned incarceration