Efficacy and Safety of Insulin Detemir in Type 1 Diabetes

Efficacy and Safety Comparison of Insulin Detemir Plus Insulin Aspart to Insulin NPH Plus Insulin Aspart in Adults With Type 1 Diabetes Mellitus

This trial is conducted in Europe.

The aim of this trial is to compare the efficacy and safety of insulin detemir and insulin NPH in adults with type 1 diabetes on blood glucose control.

Inclusion Criteria:

• Duration of type 1 diabetes for at least 12 months
• BMI below 35 kg/m2
• HbA1c between 7.0-12.0%
• Current treatment with preprandial short acting insulin and insulin NPH once or twice daily for at least 6 months
• Fertile females must use acceptable method of contraception if there is any risk of pregnancy in the opinion of the Investigator

Exclusion Criteria:

• Known or suspected allergy to trial product or related products
• Previous participation in this trial
• Receipt of any investigational products within the last 2 months prior to this trial
• Drug or alcohol dependence
• Pregnancy, breast-feeding or intention of becoming pregnant