Korean Hereditary Breast Cancer Study

Korean Hereditary Breast Cancer Study

1. To evaluate the prevalence of BRCA1/2 mutation of breast cancer patients with family history of breast/ovarian cancer.
2. To evaluate the prevalence of BRCA1/2 mutation of breast cancer patients without family history, but high risk of hereditary cancer.
3. To evaluate the prevalence of BRCA1/2 mutation of family member of BRCA1/2 mutation.
4. To evaluate the prevalence of ovarian cancer of population of above 3 groups.

1. To find founder mutation in Korean
2. To correlation prevalence with risk evaluation
3. To find risk factors concerning life style

Inclusion Criteria:

• Over 19 years old
• Agree to this study
• Breast cancer patient with family history of breast/ovarian cancer (1 subgroup)
• Breast cancer patient; young age (<40), bilateral, male, combined ovarian (2 subgroup)
• Family members with 1, 2 subgroups (3 subgroup)

Exclusion Criteria:

• Under 20 years old
• Unable to decide for oneself