International Registry and Biorepository for TMA(Thrombotic Microangiopathy)

An Observational Study of All Forms of Thrombotic Microangiopathy in Pediatric Patients

This registry will collect clinical data and store biosamples (seru, plasma, urine, and DNA) annually from pediatric patients with thrombotic mcroangiopathy

Children age, 6 months - 18 years, are eligible if they have one of the following categories of thrombotic microangiopathy (TMA):(1) severe D+HUS; (2) non-familial atypical HUS; (3) familial atypical HUS; or (4) TTP

Patients are seen intially and annually thereafter

Biosamples are collected for storage annually.

Inclusion Criteria:

• Severe HUS, familial or non-familial atypical HUS, TTP

Exclusion Criteria:

• None