A Comprehensive Study of Clinically Staged Pediatric Hodgkin's Disease: Chemotherapy for All Patients; Supplementary Low Dose Involved Field Irradiation for Selected Patients (CCG 5942)

A Comprehensive Study of Clinically Staged Pediatric Hodgkin's Disease: Chemotherapy for All Patients; Supplementary Low Dose Involved Field Irradiation for Selected Patients (CCG 5942)

Study Hypothesis: Clinical staging without laparotomy/splenectomy is adequate for children and young adults with Hodgkin's disease who receive chemotherapy as a component of treatment.

• Age less than 21 years at diagnosis
• Previously untreated, pathologically confirmed diagnosis of Hodgkin's disease.
• Informed patient/parental consent as required by individual institution and in accordance with the Dept of Health and Human Services
• Approval of this protocol by the individual institutional Human Subjects Review Committee.
• Indicate Hodgkin's disease clinical stage.
• Indicate presence or absence of "B" symptoms.
• For Stage I and II disease indicate the following:
• presence or absence of bulk disease
• number of involved nodal regions
• presence or absence of hilar adenopathy