Bone Disease in Severely Burned Children

Bone Disease in Severely Burned Children

Bone metabolism is adversely affected by severe burns in children for a period of time.

More closely monitored biochemical and radiologic parameters of bone and mineral metabolism will increase the likelihood of earlier detection of abnormalities and possible therapeutic interventions.

Inclusion Criteria:

• Children age 5-18 years old with at least 40% or more of their body burned.

Exclusion Criteria:

• Anyone with a burn covering less than 40% of the body or whose burn covers the front of both hipbones.
• Anyone younger than 5 years old, anyone with a history of cancer or other metabolic disease process, or anyone who is pregnant or has an allergy to Tetracycline will also be excluded.
• Anyone who has participated in an investigational drug trial within the past 60 days from date of admission will be excluded from this study.