Microbial Community Composition and Dynamics in Lungs of Cystic Fibrosis Sibling Pairs

Microbial Community Composition and Dynamics in Lungs of Cystic Fibrosis Sibling Pairs

The purpose of this study is to identify all the bacterial species present in the respiratory tracts of patients with Cystic Fibrosis (CF), and to connect them with clinical information. Traditional culture methods of throat swab and sputum samples can only identify the most prevalent bacteria in samples, those of which there are over about 5 million bacteria per teaspoon. A recently developed method has been found to be more sensitive and can detect up to several hundred bacterial species in throat swab or sputum sample of individual CF patients.

This study does not include testing of any investigational drugs and this is a noninvasive study requiring only a sputum/swab sample paired with information contained in the routine clinic letters and laboratory results your CF physicians obtain at your regular clinic visits.

Inclusion Criteria:

• Between the ages of 1-16 upon enrollment
• Diagnosis of Cystic Fibrosis

Exclusion Criteria:

• None