Pilot Study of 18F-FLT PET

Pilot Study of 18F-FLT Pet Imaging in Cancer Patients

Fractionated radiotherapy induces an observable change in the proliferative activity as assessed by pre-treatment and early-treatment 18F-FLT PET imaging. This study is designed to investigate 18F-FLT as a PET imaging agent for predicting treatment effectiveness in several tumors and will serve as a pilot study to a planned PO1 submission

Inclusion Criteria:

• Able to tolerate a PET/CT scan
• Age of 18 or older
• signed informed consent
• being considered for radiotherapy for treatment of CNS mets, Head and neck cancer, lung cancer, prostate cancer or esophageal cancer

Exclusion Criteria:

• Prior XRT to site being studied
• severe claustrophobia or inability to tolerate PET/CT
• unable to provide written consent
• pregnant or breastfeeding women