Memory and Insulin in Early Alzheimer's Disease

Intranasal Insulin and Memory in Early Alzheimer's Disease

To determine which parts of the brain are involved in insulin-related memory improvement in early Alzheimer's disease and cognitively normal older adults.

Functional MRI study to characterize the neuroanatomic correlates of acute exogenous insulin-related improvements in cognitive performance in early Alzheimer's disease and cognitively normal older adults. The role of the apoE-e4 allele in modulating brain insulin responses is also addressed.

Inclusion Criteria:

• Patients with Early Alzheimer's disease

Exclusion Criteria:

• Patients with Late Alzheimer's disease