The Effect of Preoperative Treatment With Mifepristone on Uterine Fibroids and Breast Tissue
The Effect of Preoperative Treatment With Mifepristone on Uterine Fibroids and Breast Tissue
Uterine fibroids are a benign but common condition among women in reproductive age. It is one of the most common reasons for hysterectomy since it often causes bleeding problems sometimes leading to anemia. Several alternative treatment regimens have been investigated that could replace surgery. The antiprogesterone, mifepristone, is one of the most promising drugs that have been tested. In addition to the inhibiting effect on the growth of uterine fibroids antiprogestins have been proposed to have an antiproliferative effect on breast tissue.
The purpose of the present study is to evaluate the effect of mifepristone on the volume of uterine fibroids. The study will also address the effect of mifepristone on the breast tissue
Other purposes of this study include:
Inclusion Criteria:
Uterine fibroids requiring treatment
Exclusion Criteria:
Criteria for retrospective exclusion:
Subjects may be excluded from analysis if one of the following applies: