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Management decision
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The purpose of the study is to determine whether Moxidex ophthalmic solution is safe and effective in treating marginal corneal infiltrates.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Moxidex | Experimental | Moxifloxacin/dexamethasone phosphate ophthalmic solution, one drop in cul-de-sac and 4 drops on closed lids of study eye(s), four times a day, for seven days |
|
| Moxifloxacin | Active Comparator | Moxifloxacin ophthalmic solution 0.5%, one drop in cul-de-sac and 4 drops on closed lids of study eye(s), four times a day, for seven days |
|
| Dexamethasone | Active Comparator | Dexamethasone phosphate solution, 0.1%, one drop in cul-de-sac and 4 drops on closed lids of study eye(s), four times a day, for seven days |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Moxifloxacin/dexamethasone phosphate ophthalmic solution | Drug |
|
| |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of patients with resolution of all corneal stromal infiltrate(s) in study eye at Test of Cure (TOC) Visit (Day 10) | Day 10 |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of patients with eradication of pre-therapy pathogens from the lid of the study eye at TOC Visit (Day 10) | Day 10 |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Contact Alcon Call Center at 1-888-451-3937 | Fort Worth | Texas | 76134 | United States |
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| Moxifloxacin ophthalmic solution 0.5% |
| Drug |
|
| Dexamethasone phosphate solution, 0.1% | Drug |
|
| ID | Term |
|---|---|
| D003316 | Corneal Diseases |
| D007249 | Inflammation |
| D001762 | Blepharitis |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D005141 | Eyelid Diseases |
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| ID | Term |
|---|---|
| D000077266 | Moxifloxacin |
| ID | Term |
|---|---|
| D024841 | Fluoroquinolones |
| D042462 | 4-Quinolones |
| D015363 | Quinolones |
| D011804 | Quinolines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006571 | Heterocyclic Compounds |
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