To determine the response rate, complete and partial, of patients with indolent lymphoma receiving Rituxan and BEAM with autologous stem cell transplant.

Objectives: I. To determine the response rate, complete and partial, of patients with indolent lymphoma receiving Rituxan and BEAM with autologous stem cell transplant. II. To determine if the addition of Rituxan changes the toxicity profile attributed to high-dose BEAM chemotherapy.

This protocol is a phase I/II trial combining the Rituxan as a pre and post-transplant agent to aid in the chemotherapy sensitization and the treatment of minimal residual disease post-transplant.

Inclusion Criteria:

• Any low-grade B-cell, CD20 positive, non-Hodgkin's lymphoma that is felt to otherwise be a transplant candidate (relapsed, induction failure, first PR or CR).

  o Small lymphocytic, marginal zone, mantle cell, and follicular histologies.

• At least 19 years of age

• Signed written informed consent

• Expected survival of at least 6 months

• WHO performance status greater or equal to 2

• Male or female subjects of reproductive potential who are able to follow accepted birth control measures.

Exclusion Criteria:

• No history of T-cell lymphoma
• Not pregnant or lactating women
• No serious disease or condition that, in the opinion of the investigator, would compromise the subject's ability to participate in the study