Montreal Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device

A Single-Center, Open-Label, Single-Arm Pilot Study of the Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Implantable Device Used to Reduce Mitral Valve Regurgitation.

Reduction in mitral regurgitation due to safe placement of a PTMA device in the coronary sinus.

Inclusion Criteria:

• Functional MR 2+ - 4+ with left ventricular enlargement
• Symptomatic heart failure
• 20% - 50% LVEF

Exclusion Criteria:

• mitral regurgitation of organic origins
• recent cardiac interventions
• severe comorbidities