Prevalence of the Metabolic Syndrome in SPR Taking Antipsychotics

Prevalence of the Metabolic Syndrome in Patients With Schizophrenia Taking Antipsychotics

The purpose of this study is to assess the cross-sectional prevalence of the metabolic syndrome in patients with schizophrenia taking antipsychotics.

Schizophrenic patients taking any kind of antipsychotics for at least 1 year at the Seoul National Hospital will be participated in this study.

we are planning to enroll approximately 1000 patients with schizophrenia.

For each subject

• abdominal circumference
• body mass index
• lipid profile : TG, HDL-chlo, total chol
• systolic/diastolic blood pressure
• fasting blood glucose will be measured.

we will calculate the rates of patients who meet the criteria for the Metabolic syndrome.

1. Abdominal obesity : absolute criteria

2. 2 or more of followings

   1. Triglyceride ≥ 150mg/dL or ongoing treatment
   2. HDL-cholesterol < 40mg/dL (men) HDL-cholesterol < 50mg/dL (female) or ongoing treatment
   3. Hypertension 130mmHg ≥ systolic 85mmHg ≥ diastolic or ongoing treatment
   4. FBS ≥ 100mg/dL or previous diagnosis of type II DM

Inclusion Criteria:

• Patients taking a same antipsychotics at least more than one year
• schizophrenia or schizoaffective disorder

Exclusion Criteria:

• none