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| Name | Class |
|---|---|
| Merck Sharp & Dohme LLC | INDUSTRY |
| Aerocrine AB | INDUSTRY |
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Asthma is a chronic inflammatory condition in which the airways develop increased responsiveness to various stimuli such as exposure to an allergen, cold air or exercise. It is characterized by airway hyper-responsiveness, inflammation, increased mucus production, and airway obstruction. Since inflammation is an important feature of asthma, the use of non-invasive tests to measure lung inflammation to monitor asthma are of interest.The purpose of the study is to relate costs associated with healthcare utilization and loss of work and school time to the primary health outcome of cumulative number of symptom-free days. This will enable the researchers to determine whether the costs of monitoring exhaled NO to regular management strategy in recently diagnosed asthma will be offset by reductions in other costs of asthma-related care, and, if not, whether the additional costs are likely to be acceptable in terms of the improvement in health outcomes as measured by the additional number of symptom-free days.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| FeNO group | asthma patients, exhaled NO is used to monitor asthma |
| |
| Symptom group | asthma patients, exhaled NO is not used to monitor asthma |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| measurement of exhaled NO is used to guide treatment | Device | exhaled NO |
|
| Measure | Description | Time Frame |
|---|---|---|
| symptom-free days | 1 year time frame with visits every 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| days spent in hospital,emergency room visits,physician or nurse contacts use of drugs, days on which school was missed, number of exacerbations | 1 year time frame |
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Inclusion Criteria:
Exclusion Criteria:
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asthmatic children
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| Name | Affiliation | Role |
|---|---|---|
| kristine N Desager, PhD | University Hospital, Antwerp | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Antwerp | Antwerp | 2650 | Belgium | |||
| Algemeen Ziekenhuis St Jan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24039119 | Derived | Peirsman EJ, Carvelli TJ, Hage PY, Hanssens LS, Pattyn L, Raes MM, Sauer KA, Vermeulen F, Desager KN. Exhaled nitric oxide in childhood allergic asthma management: a randomised controlled trial. Pediatr Pulmonol. 2014 Jul;49(7):624-31. doi: 10.1002/ppul.22873. Epub 2013 Sep 4. |
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| ID | Term |
|---|---|
| D001249 | Asthma |
| ID | Term |
|---|---|
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
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| Bruges |
| 8000 |
| Belgium |
| Univ des enfants Reine Fabiola | Brussels | 1020 | Belgium |
| Hôpital Erasme | Brussels | Belgium |
| Virga Jesseziekenhuis | Hasselt | 3500 | Belgium |
| Algemeen ziekenhuis Turnhout, Campus Sint-Jozef | Turnhout | Belgium |
| CH Peltzer | Verviers | 4800 | Belgium |
| D012130 |
| Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |