Pharmacokinetic Drug Interaction Study With Dapagliflozin and Glimepiride in Healthy Subjects

Pharmacokinetic Drug Interaction Study With Dapagliflozin and Glimepiride in Healthy Subjects

The purpose of the study is to determine the effect of glimepiride on dapagliflozin and the effect of dapagliflozin on glimepiride in healthy volunteers. In addition, the safety and tolerability of dapagliflozin with be assessed alone and while taking glimepiride

Inclusion Criteria:

• Healthy subjects with BMI of 18-32 kg/m2

Exclusion Criteria:

• Abnormal physical or lab findings
• Allergies to any sulfonylurea or related compounds