Finding out how fast azelastine nasal spray works in subjects with hay fever.

Inclusion Criteria:

• History of seasonal allergic rhinitis to ragweed pollen for last 2 consecutive seasons;
• Positive response to skin prick test to ragweed allergen at screening;
• Be willing to participate in the trial.

Exclusion Criteria:

• History of hypersensitivity to azelastine;
• Females who are pregnant or lactating;
• Relative chronic sinusitis or nasal structural abnormalities causing greater than 50% obstruction;
• Asthma that requires other than occasional use of inhaled short-acting beta-2 antagonist;
• Known non-responsiveness to antihistamines;
• Alcoholism or drug abuse within 2 yrs. of screening;
• Current or regular use within 6 months of any type of tobacco product;
• Evidence of any clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic or malignancies within the last 5 years;
• History of a positive test to HIV, TB, hepatitis B or C.