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| ID | Type | Description | Link |
|---|---|---|---|
| 885/02 |
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| Name | Class |
|---|---|
| University of Sao Paulo | OTHER |
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To test the association between anti-Chlamydia serum titers and anti-Mycoplasma antibodies with Acute Coronary Syndromes.
One hundred and twenty-six patients were divided into 4 groups: Acute Coronary Syndrome with ST-elevation, Non-ST-elevation, stable coronary artery disease, and individuals without coronary disease. Anti-Chlamydia and anti-Mycoplasma IgG antibodies were measured at baseline and after 6 months.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | ST-elevation acute myocardial infarction. |
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| 2 | high-risk unstable angina or non-ST-elevation myocardial infarction. |
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| 3 | known coronary artery disease, either asymptomatic or with stable angina. |
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| 4 | blood donors without known coronary artery disease. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| blood sample analysis - mycoplasma and chlamydia antibodies | Other | Anti-Chlamydia and anti-Mycoplasma IgG antibodies were measured by indirect immunofluorescence at baseline (24 hours of hospitalization) and after 6 months (follow-up). |
| Measure | Description | Time Frame |
|---|---|---|
| Test the hypothesis that patients with acute coronary syndromes have higher levels of Chlamydia pneumonia and Mycoplasma pneumonia antibodies in comparison with patients with stable coronary artery disease or controls. | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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Group 1 and 2 - selected after admission in coronary care unit. Group 3 - selected from out-patient cardiology clinic. Group 4 - selected from the blood donation unit.
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| Name | Affiliation | Role |
|---|---|---|
| Jose C Nicolau, MD, pHD | University of Sao Paulo | Study Director |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19629306 | Derived | Maia IL, Nicolau JC, Machado MN, Maia LN, Takakura IT, Rocha PR, Cordeiro JA, Ramires JA. Prevalence of Chlamydia pneumoniae and Mycoplasma pneumoniae in different forms of coronary disease. Arq Bras Cardiol. 2009 Jun;92(6):405-11, 422-8, 439-45. doi: 10.1590/s0066-782x2009000600005. English, Multiple languages. |
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| ID | Term |
|---|---|
| D050197 | Atherosclerosis |
| D003324 | Coronary Artery Disease |
| D002690 | Chlamydia Infections |
| D009175 | Mycoplasma Infections |
| ID | Term |
|---|---|
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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Blood sample - serum
| D003327 |
| Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002694 | Chlamydiaceae Infections |
| D016905 | Gram-Negative Bacterial Infections |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
| D015231 | Sexually Transmitted Diseases, Bacterial |
| D012749 | Sexually Transmitted Diseases |
| D003141 | Communicable Diseases |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D009180 | Mycoplasmatales Infections |