Nutritional and Metabolic Evaluation of a Tube Feeding Immune Enhancing Diet in ICU Patients

Nutritional and Metabolic Evaluation of a Tube Feeding Immune Enhancing Diet in ICU Patients

Comparison of metabolic and nutritional effects of an enteral immune enhancing diet with those of a standard polymeric one, in ICU patients

Inclusion Criteria:

• 18<age<89, ASA score<4 , SAPS II score>10
• requiring the administration of an exclusive tube feeding nutrition during 7 days and beginning at the latest in the three days following the aggression
• ICU patients hospitalized for:
• neurologic affections
• pneumopathy
• major abdominal surgery or serious acute pancreatitis
• written informed consent

Exclusion Criteria:

• pregnancy or breast feeding
• immunosuppressive therapy
• radiotherapy or chemotherapy in the last six month
• uncontrolled septic choc
• auto-immune disease
• hepatic,renal or digestive insufficiency
• hyperlipidemia
• diabetes mellitus type 1
• digestive malabsorption
• life threatening situation
• treatments with growing hormone, glutamine or its metabolites or precursors such as ornithine alpha keto glutarate