Evaluate the benefit (rate of adherence to the treatment), based on the LDL-C reduction in the group that will be exposed to the program of reinforcement of orientation aimed to the patients, compared to the control group, both in previous use of rosuvastatin.

Inclusion Criteria:

• Subjects eligible for the treatment of dyslipidemia with statins according the current guidelines NCEP ATPIII and IV Brazilian Guidelines of Dyslipidemia and Atherosclerosis Prevention.
• Patients with previous use of rosuvastatin for, at least, 15 days and, for no longer than12 months prior to the inclusion in the study.

Exclusion Criteria:

Pregnancy and childbearing

• History of severe hypersensitivity (including myopathy) to other HMG-CoA reductase inhibitors.
• Subjects with indication of use of cyclosporine and other associations of other lipid lowering drugs.
• Subjects with underlying diseases that may influence lipid levels (i.e. uncontrolled hypothyroidism defined as a Thyroid stimulating hormone (TSH) > 1.5 times upper level of normality (ULN) at Visit 1, AIDS, transplanted subjects, etc).
• History of drug and alcohol abuse.
• Current active liver disease or hepatic failure or elevations in ALT >3 times the ULN.
• Elevation of CPK > 3 times the ULN.
• Elevation in the seric creatinine > 2,0 mg / dL.
• History of malignancy in the last 5 years, except basal cell or squamous cell carcinoma of the skin (women with a history of Cervical dysplasia must be included, unless they have t3 clear consecutive Papanicolaou (Pap) smears , before the entry in the study).
• Any other known clinical condition that, in the opinion of the investigator, may compromise the subject's safety.

Primary Care Clinic