Trial on Metoclopramide and Ketoprofen in Acute Migraine of Childhood

Randomized Controlled Trial on the Effectiveness of Metoclopramide Alone or in Combination With Ketoprofen in Acute Migraine of Child

This is a Randomized double blind trial with the aim to estimate the effectiveness of 3 therapeutic regimes per os on migraine pain:

• metoclopramide 0,15 mg/kg + placebo
• metoclopramide 0,15 mg/Kg + ketoprofen 1 mg/kg
• ketoprofen 1 mg/Kg + placebo

Intensity of pain will be measured with linear 1-10 scale or analogic McGrath type scale every 20 min.

The main objective is the evaluation of healing times from pain in the 3 groups

Inclusion Criteria:

• Children 6-17 years old with migraine presenting in emergency room

Exclusion Criteria:

• Informed consensus not obtained
• Occurring migraine still treated
• Hemiplegic migraine