to investigate the safety and pharmacokinetics, in healthy adult male subjects

Safety and Pharmacokinetics of Probucol and Cilostazol when co-administered in Health Subjects

Inclusion Criteria:

• Korean
• Gender: Male
• Age: Over 20 and Under 40years, at time of informed consent
• body weight: BMI over 19.0 and Under 25.0
• Subjects who meet the following criteria at the time of the screening examination
• Subjects who have given their written informed consent prior to participation in the study
• Subjects who are reliable and willing to make themselves available for the duration of the study and follow the study protocol

Exclusion Criteria:

• History or clinical evidence of significant respiratory, cardiovascular, renal, gastrointestinal, hepatic, endocrine, hematologic, neurologic, psychiatric, or other chronic disease, alcoholism, or drug abuse
• Present or previous significant drug allergy to any prescription or over the counter medication
• Blood collection exceeding 200ml within 4 weeks, 400ml within 12 weeks, or 1200ml within one year prior to scheduled study drug administration
• Body weight: under 50Kg