A First Time in Human Study in Healthy Male Volunteers for Compound GSK557296.

A Two-Part Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Repeat Oral Doses of GSK557296 in a Randomized, Single-Blind, Placebo-Controlled, Dose-Rising Design, and to Evaluate the Effect of Food on Single Oral Doses of GSK557296 in Healthy Adult Subjects

A study conducted on healthy volunteers to determine the safety, tolerability and affect on the human body by experimental drug GSK557296.

Inclusion Criteria:

• Healthy males who are 18 to 45 years of age
• Body mass index between 19 and 30 with a body weight greater than 110 pounds and deemed healthy by a physician
• Non-smokers

Exclusion Criteria:

• Alcohol consumption averaging more than 7 drinks per week
• Positive for Hepatitis C antibody, Hepatitis B antigen or HIV
• Any use of prescription drugs or non prescription drugs