Chronic Obstructive Pulmonary Disease (COPD) Nutrition Support Trial

A Randomised Trial of Oral Nutritional Supplements Versus Dietary Advice on Clinical Outcomes in Patients With COPD

The purpose of this study is to determine the best form of dietary intervention to undernourished individuals with COPD.

The research aims to test the null hypothesis that there is no difference between oral nutritional supplements and dietary advice.

Inclusion Criteria:

• Male or female
• Age >18 years
• At risk of malnutrition
• Competent to provide written informed consent and able to answer questions
• Able to eat and drink
• Willingness to take part in the trial and to follow the trial protocol
• FEV1 <80% predicted and FEV1/FVC <0.7

Exclusion Criteria:

• Requirement for tube or parenteral nutrition
• Galactosemia
• Receiving current oral nutritional supplementation
• Palliative care
• Chronic renal disease requiring dialysis
• Liver failure
• Malignancy
• Participation in other studies
• Bronchiectasis
• Those already under the care of a dietitian