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Retrospective studies have shown, that about half of the patients will have a recurrent episode after the first acute alcoholic pancreatitis. Of the patients in hospital, more than half annually are treated for recurrent acute pancreatitis. Because alcohol has been shown an important factor in the development of recurrent pancreatitis, it was hypothesized, that by attempting intensively to diminish the individual alcohol consumption the number of recurrent pancreatitis could be decreased. Two protocols will be compared: A) initial intervention against alcohol abuse and B) repeated interventions at 6 month intervals.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Active Comparator | All these patients will be advised, i.e. undergo behavioural intervention, against alcohol use in the standard fashion. No drugs will be used. In addition, they also will undergo repeated similar interventions at 6 mo intervals. They are re-examined at two years for alcohol consumption and for the number of recurrent pancreatitis during the two year period. |
|
| Standard | No Intervention | All these patients will be advised, i.e. undergo behavioural intervention, against alcohol use in the standard fashion. No drugs will be used. They are re-examined at two years for alcohol consumption and for the number of recurrent pancreatitis during the two year period. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Repeated behavioural intervention without any drugs | Behavioral | All these patients will be advised, i.e. undergo "behavioural intervention", against alcohol use in the standard fashion as those in the standard group. No drugs will be used as part of the intervention. They also will undergo repeated interventions at outpatient visits at 6 mo intervals. They are re-examined at two years for alcohol consumption and for the number of recurrent pancreatitis during the two year period. |
| Measure | Description | Time Frame |
|---|---|---|
| The number of recurrent pancreatitis during the study period | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Decrease of alcohol consumption | 2 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Isto H Nordback, M.D. | Tampere University Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tampere University Hospital | Tampere | 33521 | Finland |
| Type | Date | Date Unknown |
|---|---|---|
| Release | Feb 20, 2009 | |
| Reset | Mar 13, 2009 | |
| Release | Jan 12, 2010 | |
| Reset | Feb 3, 2010 | |
| Release | Dec 18, 2013 | |
| Reset | Feb 7, 2014 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Feb 20, 2009 | Mar 13, 2009 | |||
| Jan 12, 2010 |
| ID | Term |
|---|---|
| D010195 | Pancreatitis |
| D012008 | Recurrence |
| D000437 | Alcoholism |
| ID | Term |
|---|---|
| D010182 | Pancreatic Diseases |
| D004066 | Digestive System Diseases |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
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|
| Feb 3, 2010 |
| Dec 18, 2013 | Feb 7, 2014 |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D019973 | Alcohol-Related Disorders |
| D019966 | Substance-Related Disorders |
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |