Single-Dose Safety Study of APD791 in Healthy Volunteers

A Randomized, Double-Blind, Placebo-Controlled, Single-Dose Escalation Study to Assess the Tolerability, Pharmacokinetics, and Pharmacodynamics of APD791 Administered to Healthy Adult Subjects

The APD791-001 study is designed primarily to evaluate the safety and tolerability of APD791 when administered as a single oral dose to healthy adult subjects.

Inclusion Criteria:

• Healthy adult men and women, ages 19-45
• Non smokers

Exclusion Criteria:

• History of a bleeding disorder
• Recently donated blood or had significant blood loss
• Current use of a prescription medication
• Pregnant females