The purpose of this study is to determine whether the improvement in the quality of life after an initial treatment with esomeprazole 40mg for reflux disease is the same in patients who have already made lifestyle-adjustments as in patients who have not implemented lifestyle-adjustments prior to the start of treatment (baseline)

Inclusion Criteria:

• Patients with reflux complaints
• 18 years of age

Exclusion Criteria:

• Restrictions as mentioned in the registration text
• H2RA or PPI use in the month prior to inclusion