Bromfenac 0.09% vs Ketorolac 0.4% for Cyclosporine Induction Phase

Bromfenac 0.09% vs. Ketorolac 0.4% During the Induction Phase of Treatment With Topical Cyclosporine for Chronic Dry Eye Patients

To compare bromfenac 0.09% and ketorolac 0.4% when used concomitantly with cyclosporine ophthalmic emulsion 0.05% in improving patient comfort during the induction phase of treatment for chronic dry eye disease

Inclusion Criteria:

• Must be in general good health
• Diagnosis of moderate to severe dry eye syndrome

Exclusion Criteria:

• Patients who are unlikely to respond to cyclosporine ophthalmic emulsion therapy
• Patients who are pregnant or nursing females
• Unwilling to discontinue use of contact lenses during the run-in and duration of the study
• Presence or history of any systemic or ocular disorder or condition that could possibly interfere with the interpretation of the study results in the study eye
• Previous treatment failure on CSA 0.05% (Restasis)
• Known hypersensitivity to any component of the study or procedural medications
• Participation in any other clinical trial within 30 days prior to screening
• Known contraindication to any study medication or any of their components.
• Should not be taking any oral anti-histamines, beta blockers or diuretics.