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| Name | Class |
|---|---|
| Lund University | OTHER |
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The purpose of this study is to compare how effective different ways of mouth cleaning are for patients in a neuroscience intensive care unit with a breathing tube in their mouth.
Patients with neurological dysfunction requiring intubation and ventilation are at risk for developing ventilator acquired pneumonia. Several studies have suggested that oral hygiene plays a role in the subsequent development of pneumonia for patients in the intensive care unit requiring intubation and mechanical ventilation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A | Active Comparator | Standard Oral Care |
|
| B | Experimental | Comprehensive Oral Care |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Standard Oral Care | Procedure | Patients in this arm will receive standard oral care with manual brushes and routine oral hygiene products twice a day |
|
| Measure | Description | Time Frame |
|---|---|---|
| Development of Ventilator Acquired Pneumonia | During the period of intubation |
| Measure | Description | Time Frame |
|---|---|---|
| Improved Oral Health | During the period of intubation and 48 hours following extubation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Virginia C Prendergast, MSN, NP-C | St Joseph's Hospital and Medical Center, Phoenix, Arizona, USA | Principal Investigator |
| Ingalill R Hallberg, PhD | Vardalinstitutet, University of Lund, Sweden | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| St. Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 14735645 | Background | Munro CL, Grap MJ. Oral health and care in the intensive care unit: state of the science. Am J Crit Care. 2004 Jan;13(1):25-33; discussion 34. | |
| 12626984 | Background | Dennesen P, van der Ven A, Vlasveld M, Lokker L, Ramsay G, Kessels A, van den Keijbus P, van Nieuw Amerongen A, Veerman E. Inadequate salivary flow and poor oral mucosal status in intubated intensive care unit patients. Crit Care Med. 2003 Mar;31(3):781-6. doi: 10.1097/01.CCM.0000053646.04085.29. |
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| ID | Term |
|---|---|
| D053717 | Pneumonia, Ventilator-Associated |
| D014987 | Xerostomia |
| ID | Term |
|---|---|
| D000077299 | Healthcare-Associated Pneumonia |
| D003428 | Cross Infection |
| D007239 | Infections |
| D011014 | Pneumonia |
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| Comprehensive Oral Care | Procedure | Patients will receive a comprehensive oral care protocol using mechanical brushes and oral care products formulated for patients with a dry mouth twice a day |
|
| 21249529 | Derived | Prendergast V, Hagell P, Hallberg IR. Electric versus manual tooth brushing among neuroscience ICU patients: is it safe? Neurocrit Care. 2011 Apr;14(2):281-6. doi: 10.1007/s12028-011-9502-2. |
| D012141 |
| Respiratory Tract Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D007049 | Iatrogenic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012466 | Salivary Gland Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |