Genetic Abnormalities and Biological Changes of Panic Disorder Patients After Pharmacotherapy

Genetic Abnormalities and Changes of Autonomic Nervous System, Serotonin System, and Neuroendocrine System According to Pharmacotherapy in Panic Disorder

We plan to examine genetic polymorphism of catechol-O-methyltransferase in panic disorder and neurobiological changes of panic disorder patients after 12 weeks of pharmacotherapy with paroxetine. We plan to include 40 panic disorder patients and 40 normal control subjects in this study for 3 years.

Inclusion Criteria:

• Panic disorder

Exclusion Criteria:

• Other major medical or psychiatric illnesses