Development of a Predictive Model for Post-Discharge Nausea and Vomiting (PDNV)

Development of a Predictive Model for Post-Discharge Nausea and Vomiting (PDNV)

The primary purpose of this prospective cohort study is to develop a simplified risk model for post-discharge nausea and vomiting (PDNV) in adult same-day surgery patients in the US that will allow clinicians to identify those patients who would benefit from prophylactic antiemetic strategies.

Inclusion Criteria:

• 18 years of age or older
• scheduled for an elective outpatient surgical procedure
• understands the nature and purpose of this survey and has signed an informed consent form
• willing and able to complete daily components of the Patient Diary from the day of surgery until the end of the 48 hour assessment
• undergoing general anesthesia requiring a tracheal tube or laryngeal mask airway

Exclusion Criteria:

• planned inpatient surgery
• inability to communicate in English
• regional anesthesia alone without general anesthesia, as PONV in this setting is known to be significantly lower [18, 19]
• persistent or recurrent nausea and/or vomiting before anesthesia due to other etiologies, unless clearly related only to the anxiety due to impending surgery
• minors (< 18 years of age)
• current pregnancy by self-report (potentially confounding for etiology of nausea)