Sitagliptin Versus Glipizide in Participants With Type 2 Diabetes Mellitus and Chronic Renal Insufficiency (MK-0431-063 AM1)

A Multicenter, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Sitagliptin Versus Glipizide in Patients With Type 2 Diabetes Mellitus and Chronic Renal Insufficiency Who Have Inadequate Glycemic Control

The purpose of the study is to compare how sitagliptin and glipizide lower blood glucose levels in participants with moderate or severe renal insufficiency.

Inclusion Criteria:

• Has type 2 diabetes mellitus
• Has moderate or severe renal insufficiency

Exclusion Criteria:

• Has type 1 diabetes mellitus or a history of ketoacidosis
• Is on a new weight loss program
• Has active liver disease
• Is on dialysis or is likely to need dialysis during the study